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Delayed potassium rectifier current

KCNQ1
Protein CD44 PDB 1poz.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases KCNQ1, ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, KVLQT1, Kv1.9, Kv7.1, LQT, LQT1, RWS, SQT2, WRS, potassium voltage-gated channel subfamily Q member 1
External IDs OMIM: 607542 MGI: 108083 HomoloGene: 85014 GeneCards: KCNQ1
Genetically Related Diseases
type 2 diabetes mellitus
Targeted by Drug
mefenamic acid, niflumic acid
RNA expression pattern
PBB GE CD44 204489 s at tn.png

PBB GE CD44 204490 s at tn.png

PBB GE CD44 212063 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_181798
NM_000218
NM_181797

NM_008434

RefSeq (protein)

NP_000209
NP_861463

NP_032460.2
NP_032460

Location (UCSC) Chr 11: 2.44 – 2.85 Mb Chr 7: 143.11 – 143.43 Mb
PubMed search

3BJ4, 3HFC, 3HFE, 4UMO, 4V0C

NM_181798
NM_000218
NM_181797

NM_008434

NP_000209
NP_861463

NP_032460.2
NP_032460

Kv7.1 (KvLQT1) is a potassium channel protein whose primary subunit in humans is encoded by the KCNQ1 gene. Kv7.1 is a voltage-gated potassium channel present in the cell membranes of cardiac tissue and in inner ear neurons among other tissues. In the cardiac cells, Kv7.1 mediates the IKs (or slow delayed rectifying K+) current that contributes to the repolarization of the cell, terminating the cardiac action potential and thereby the heart's contraction.


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