DNMT1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4YOC, 3EPZ, 3PTA, 3SWR, 4WXX

Identifiers

DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT, m.HsaI, DNA (cytosine-5-)-methyltransferase 1, DNA methyltransferase 1

External IDs

Gene ontology
Molecular function	• methyltransferase activity • DNA binding • transferase activity • promoter-specific chromatin binding • methyl-CpG binding • zinc ion binding • DNA-methyltransferase activity • chromatin binding • metal ion binding • protein binding • RNA binding • DNA (cytosine-5-)-methyltransferase activity
Cellular component	• pericentric heterochromatin • replication fork • nucleoplasm • heterochromatin • nucleus
Biological process	• gene silencing • C-5 methylation of cytosine • regulation of transcription, DNA-templated • maintenance of DNA methylation • positive regulation of methylation-dependent chromatin silencing • negative regulation of transcription from RNA polymerase II promoter • transcription, DNA-templated • methylation • DNA methylation • positive regulation of gene expression • negative regulation of gene expression, epigenetic • positive regulation of histone H3-K4 methylation • regulation of cell proliferation • negative regulation of histone H3-K9 methylation • cellular response to amino acid stimulus • regulation of gene expression • Ras protein signal transduction • negative regulation of transcription, DNA-templated • covalent chromatin modification • DNA methylation on cytosine • DNA methylation involved in embryo development
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


1786


13433


ENSG00000130816


ENSMUSG00000004099


P26358


P13864

RefSeq (mRNA)


NM_001130823 NM_001379 NM_001318730 NM_001318731


NM_001199431 NM_001199432 NM_001199433 NM_010066 NM_001314011

RefSeq (protein)


NP_001124295 NP_001305659 NP_001305660 NP_001370

NP_001186360.2 NP_001186361.1 NP_001186362.1 NP_034196.5 NP_001300940.1
NP_001186360 NP_001186361 NP_001186362 NP_001300940 NP_034196

Location (UCSC)

PubMed search