DLG2

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2BYG, 2HE2

Identifiers

Aliases

DLG2, PPP1R58, PSD-93, PSD93, chapsyn-110, discs large homolog 2, discs large MAGUK scaffold protein 2

External IDs

MGI: 1344351 HomoloGene: 1046 GeneCards: DLG2

Genetically Related Diseases

obesity, nephroblastoma, Parkinson's disease

Gene ontology
Molecular function	• guanylate kinase activity • kinase binding • protein binding • ionotropic glutamate receptor binding
Cellular component	• postsynaptic membrane • cell projection • membrane • postsynaptic density • voltage-gated potassium channel complex • plasma membrane • synapse • axon • cell junction • basolateral plasma membrane • ionotropic glutamate receptor complex • juxtaparanode region of axon • cytosol
Biological process	• chemical synaptic transmission • receptor localization to synapse • negative regulation of phosphatase activity • receptor clustering • nervous system development • establishment or maintenance of epithelial cell apical/basal polarity • sensory perception of pain • GDP metabolic process • GMP metabolic process
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


1740


23859

Ensembl


ENSG00000150672


ENSMUSG00000052572

UniProt


Q15700


Q91XM9

RefSeq (mRNA)

NM_001142699 NM_001142700 NM_001142702 NM_001206769 NM_001300983
NM_001364


NM_001243046 NM_001243047 NM_011807

RefSeq (protein)

NP_001136171 NP_001136172 NP_001136174 NP_001193698 NP_001287912
NP_001355


NP_001229976.1 NP_035937.2 NP_001229975 NP_001229976 NP_035937

Location (UCSC)

Chr 11: 83.46 – 85.63 Mb

Chr 7: 91.09 – 92.45 Mb

PubMed search

NM_001243046
NM_001243047
NM_011807

NP_001355

NP_001229976.1
NP_035937.2
NP_001229975
NP_001229976
NP_035937

Disks large homolog 2 (DLG2) also known as channel-associated protein of synapse-110 (chapsyn-110) or postsynaptic density protein 93 (PSD-93) is a protein that in humans is encoded by the DLG2 gene.

...
Wikipedia