DEPTOR

DEPTOR
Identifiers
Aliases	DEPTOR, DEP.6, DEPDC6, DEP domain containing MTOR-interacting protein, DEP domain containing MTOR interacting protein
External IDs	MGI: 2146322 HomoloGene: 32551 GeneCards: DEPTOR
Gene ontology Molecular function • protein binding Cellular component • intracellular • cytoplasm Biological process • negative regulation of TOR signaling • intracellular signal transduction • regulation of extrinsic apoptotic signaling pathway • negative regulation of protein kinase activity • negative regulation of cell size Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	64798	97998
Ensembl	ENSG00000155792	ENSMUSG00000022419
UniProt	Q8TB45	Q570Y9
RefSeq (mRNA)	NM_022783 NM_001283012	NM_001037937 NM_145470
RefSeq (protein)	NP_001269941 NP_073620	NP_001033026 NP_663445
Location (UCSC)	Chr 8: 119.87 – 120.05 Mb	Chr 15: 55.11 – 55.26 Mb
PubMed search

64798

97998

ENSG00000155792

ENSMUSG00000022419

Q8TB45

Q570Y9

NM_022783
NM_001283012

NM_001037937
NM_145470

NP_001269941
NP_073620

NP_001033026
NP_663445

DEP domain-containing mTOR-interacting protein (DEPTOR) also known as DEP domain-containing protein 6 (DEPDC6) is a protein that in humans is encoded by the DEPTOR gene.

The gene DEPTOR can be found only in vertebrates. In human, DEPTOR gene locates at chromosome 8, 8q24.12 with protein size 409 a.a. Human DEPTOR contains two N-terminal DEP domains and a C-terminal PDZ domain.

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