DAZAP2

DAZAP2
Identifiers
Aliases	DAZAP2, PRTB, DAZ associated protein 2
External IDs	MGI: 1344344 HomoloGene: 8038 GeneCards: DAZAP2
Gene location (Human) Chr. Chromosome 12 (human) Band n/a Start 51,238,292 bp End 51,271,362 bp
Gene location (Mouse) Chr. Chromosome 15 (mouse) Band n/a Start 100,615,628 bp End 100,620,731 bp
RNA expression pattern More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9802	23994
Ensembl	ENSG00000183283	ENSMUSG00000000346
UniProt	Q15038	Q9DCP9
RefSeq (mRNA)	NM_014764 NM_001136264 NM_001136266 NM_001136267 NM_001136268 NM_001136269	NM_011873
RefSeq (protein)	NP_001129736 NP_001129738 NP_001129739 NP_001129740 NP_001129741 NP_055579	NP_036003
Location (UCSC)	Chr 12: 51.24 – 51.27 Mb	Chr 12: 100.62 – 100.62 Mb
PubMed search

9802

23994

ENSG00000183283

ENSMUSG00000000346

Q15038

Q9DCP9

NM_001136269

NM_011873

NP_055579

NP_036003

DAZ-associated protein 2 is a protein that in humans is encoded by the DAZAP2 gene.

In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region and is deleted in many azoospermic and severely oligospermic men. It is thought that the Y chromosomal DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL.

DAZAP2 has been shown to interact with DAZ1.

...
Wikipedia