Cystathionine beta synthase

CBS

PBB Protein CBS image.jpg

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1JBQ, 1M54, 4COO, 4L0D, 4L27, 4L28, 4L3V, 4PCU, 4UUU

Identifiers

CBS, HIP4, cystathionine-beta-synthase

External IDs

OMIM: 613381 MGI: 88285 HomoloGene: 37258 GeneCards: CBS

Genetically Related Diseases

Targeted by Drug

aminooxyacetic acid

Gene ontology
Molecular function	• oxygen binding • protein homodimerization activity • cystathionine beta-synthase activity • metal ion binding • nitric oxide binding • catalytic activity • protein binding • heme binding • modified amino acid binding • S-adenosyl-L-methionine binding • lyase activity • identical protein binding • enzyme binding • pyridoxal phosphate binding • nitrite reductase (NO-forming) activity • ubiquitin protein ligase binding • carbon monoxide binding
Cellular component	• cytoplasm • cytosol • nucleus
Biological process	• transsulfuration • cysteine biosynthetic process via cystathionine • L-serine metabolic process • DNA protection • cellular amino acid biosynthetic process • L-serine catabolic process • cysteine biosynthetic process • homocysteine catabolic process • hydrogen sulfide biosynthetic process • metabolic process • homocysteine metabolic process • L-cysteine catabolic process • oxidation-reduction process • cysteine biosynthetic process from serine
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


875


12411


ENSG00000160200


ENSMUSG00000024039


P35520


Q91WT9

RefSeq (mRNA)


NM_000071 NM_001178008 NM_001178009 NM_001320298 NM_001321072


NM_001271353 NM_144855 NM_178224

RefSeq (protein)


NP_000062.1 NP_001171479.1 NP_001171480.1 NP_001307227.1 NP_001308002.1

NP_001258282.1 NP_659104.1 NP_835742.1 NP_001258282 NP_659104
NP_835742

Location (UCSC)

Chr 21: 43.05 – 43.08 Mb

Chr 17: 31.61 – 31.64 Mb

PubMed search

cystathionine beta-synthase

Identifiers

Databases

metabolic pathway

PDB structures

RCSB PDB PDBe PDBsum

Search
PMC	articles
PubMed	articles
NCBI	proteins

Search
PMC	articles
PubMed	articles
NCBI	proteins

1JBQ, 1M54, 4COO, 4L0D, 4L27, 4L28, 4L3V, 4PCU, 4UUU

ENSG00000160200

ENSMUSG00000024039

NM_000071
NM_001178008
NM_001178009
NM_001320298
NM_001321072

NM_001271353
NM_144855
NM_178224

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Wikipedia

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