Cystathionine beta-synthase

CBS

PBB Protein CBS image.jpg

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1JBQ, 1M54, 4COO, 4L0D, 4L27, 4L28, 4L3V, 4PCU, 4UUU

Identifiers

CBS, HIP4, cystathionine-beta-synthase

External IDs

OMIM: 613381 MGI: 88285 HomoloGene: 37258 GeneCards: CBS

Gene location (Mouse)

Chr.	Chromosome 17 (mouse)

Band	No data available	Start	31,612,623 bp
Band	No data available	End	31,637,199 bp

Gene ontology
Molecular function	• oxygen binding • protein homodimerization activity • cystathionine beta-synthase activity • metal ion binding • nitric oxide binding • catalytic activity • protein binding • heme binding • modified amino acid binding • S-adenosyl-L-methionine binding • lyase activity • identical protein binding • enzyme binding • pyridoxal phosphate binding • nitrite reductase (NO-forming) activity • ubiquitin protein ligase binding • carbon monoxide binding
Cellular component	• cytoplasm • cytosol • nucleus
Biological process	• transsulfuration • cysteine biosynthetic process via cystathionine • L-serine metabolic process • DNA protection • cellular amino acid biosynthetic process • L-serine catabolic process • cysteine biosynthetic process • homocysteine catabolic process • hydrogen sulfide biosynthetic process • metabolic process • homocysteine metabolic process • L-cysteine catabolic process • oxidation-reduction process • cysteine biosynthetic process from serine
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


875


12411


ENSG00000160200


ENSMUSG00000024039


P35520


Q91WT9

RefSeq (mRNA)


n/a


NM_001271353 NM_144855 NM_178224

RefSeq (protein)


NP_000062.1 NP_001171479.1 NP_001171480.1 NP_001307227.1 NP_001308002.1


NP_001258282 NP_659104 NP_835742

Location (UCSC)

n/a

Chr 21: 31.61 – 31.64 Mb

PubMed search

cystathionine beta-synthase

Identifiers

Databases

metabolic pathway

PDB structures

RCSB PDB PDBe PDBsum

Search
PMC	articles
PubMed	articles
NCBI	proteins

Search
PMC	articles
PubMed	articles
NCBI	proteins

1JBQ, 1M54, 4COO, 4L0D, 4L27, 4L28, 4L3V, 4PCU, 4UUU

ENSG00000160200

ENSMUSG00000024039

n/a

NM_001271353
NM_144855
NM_178224

NP_000062.1
NP_001171479.1
NP_001171480.1
NP_001307227.1
NP_001308002.1

...
Wikipedia

...