Cyclin B2

CCNB2
Identifiers
Aliases	CCNB2, HsT17299, Cyclin B2
External IDs	MGI: 88311 HomoloGene: 74359 GeneCards: CCNB2
Gene ontology Molecular function • protein binding • cyclin-dependent protein serine/threonine kinase activity • cadherin binding Cellular component • microtubule cytoskeleton • centrosome • membrane • nucleus • nucleoplasm • cytosol Biological process • T cell homeostasis • thymus development • growth • cell division • cell cycle • mitotic nuclear envelope disassembly • in utero embryonic development • G2/M transition of mitotic cell cycle • regulation of cell cycle Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9133	12442
Ensembl	ENSG00000157456	ENSMUSG00000032218
UniProt	O95067	P30276
RefSeq (mRNA)	NM_004701	NM_007630
RefSeq (protein)	NP_004692	NP_031656.2 NP_031656
Location (UCSC)	Chr 15: 59.11 – 59.13 Mb	Chr 9: 70.41 – 70.42 Mb
PubMed search

9133

12442

ENSG00000157456

ENSMUSG00000032218

O95067

P30276

NM_004701

NM_007630

NP_004692

NP_031656.2
NP_031656

G2/mitotic-specific cyclin-B2 is a protein that in humans is encoded by the CCNB2 gene.

Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.

Cyclin B2 has been shown to interact with TGF beta receptor 2.

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Wikipedia