Cyclin-dependent kinase 3

CDK3
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 1LFN
Identifiers
Aliases	CDK3
External IDs	HomoloGene: 74387 GeneCards: CDK3
Gene ontology Molecular function • protein serine/threonine kinase activity • ATP binding • kinase activity • nucleotide binding • protein kinase activity • transferase activity • cyclin-dependent protein serine/threonine kinase activity • protein binding • cyclin binding Cellular component • cyclin-dependent protein kinase holoenzyme complex • nucleus • cytoplasm Biological process • cell division • cell proliferation • G1/S transition of mitotic cell cycle • cell cycle • G0 to G1 transition • cellular response to DNA damage stimulus • phosphorylation • protein phosphorylation • signal transduction • multicellular organism development • positive regulation of cell proliferation • response to organic substance • regulation of G2/M transition of mitotic cell cycle • regulation of gene expression Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1018	n/a
Ensembl	ENSG00000261408	n/a
UniProt	Q00526	n/a
RefSeq (mRNA)	NM_001258	n/a
RefSeq (protein)	NP_001249	n/a
Location (UCSC)	Chr 17: 75.98 – 76.01 Mb	n/a
PubMed search		n/a

1LFN

1018

n/a

ENSG00000261408

n/a

Q00526

n/a

NM_001258

n/a

NP_001249

n/a

Cell division protein kinase 3 is an enzyme that in humans is encoded by the CDK3 gene.

CDK3 complements cdc28 mutants of Saccharomyces cerevisiae suggesting that it may be involved in cell cycle control. CDK3 can phosphorylate histone H1 and interacts with an unknown type of cyclin.

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