The Cybo, Cibo or Cibei family of Italy is an aristocratic family from Genoa of Greek origin. They came to the city in the 12th century. In 1528 the Cybos formed the 17th "Albergo", a union of noble families of Genoa. The family split in many branches, some living in Genoa, other in Naples by the name of Tomacelli. Its most famous members were Pope Boniface IX. and Pope Innocent VIII.
The Cybo married with the most famous Italian families including Medici of Tuscany, Della Rovere of Urbino and Este of Modena and had blood relationship with the noble banking family Altoviti. Innocent VIII was the uncle of La Papessa Dianora Cybo Altoviti and her son Bindo Altoviti was a close ally of his cousin cardinal Innocenzo Cybo, one of the most influential bankers and patron of the arts of the Renaissance.
Innocent VIII illegitimate son was Franceschetto Cybo, son in law to Lorenzo Il Magnifico de' Medici and brother-in-law to Pope Leo X. He was given by his father the title of Count of the Lateran Palace. Later Pope Julius II award him with the title Duke of Spoleto. His son Lorenzo Cybo, married Ricciarda Malaspina d'Este and became marquis of Massa and Carrara, founding the Cybo-Malaspina branch, later elevated to the dukes of Massa and Carrara.
Notable members from the 15th century to the 19th century include: