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Cyanocobalamin

Cyanocobalamin
Cyanocobalamin.svg
Cyanocobalamin-3D-sticks.png
Identifiers
68-19-9 YesY
ChEMBL ChEMBL1200658 N
DrugBank DB00115 YesY
ECHA InfoCard 100.000.618
EC Number 200-680-0
V09XX01 (WHO) (57Co)
V09XX02 (WHO) (58Co)
UNII P6YC3EG204 YesY
Properties
C63H88CoN14O14P
Molar mass 1355.38 g/mol
Appearance Dark red solid
Melting point > 300 °C
Boiling point > 300 °C
1g/80ml
Solubility soluble in alcohol, insoluble in acetone and chloroform
Pharmacology
B03BA01 (WHO)
Hazards
Safety data sheet External MSDS from Fisher Scientific
Not available
S-phrases S24/25
NFPA 704
Flammability code 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g., canola oil Health code 1: Exposure would cause irritation but only minor residual injury. E.g., turpentine Reactivity code 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g., liquid nitrogen Special hazards (white): no codeNFPA 704 four-colored diamond
Flash point N/A
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YesYN ?)
Infobox references

Cyanocobalamin is a synthetic form of vitamin B
12
. Vitamin B
12
is the "generic descriptor" name for any vitamers of vitamin B
12
. Because humans and animals can convert cyanocobalamin to any one of the active vitamin B
12
compounds, by definition this makes cyanocobalamin itself a form (or vitamer) of B
12
.

Cyanocobalamin is usually prescribed after surgical removal of part or all of the stomach or intestine to ensure adequate serum levels of vitamin B
12
. It is also used to treat pernicious anemia, vitamin B
12
deficiency (due to low intake from food), thyrotoxicosis, hemorrhage, malignancy, liver disease and kidney disease. Cyanocobalamin injections are often prescribed to gastric bypass patients who have had part of their small intestine bypassed, making it difficult for B
12
to be acquired via food or vitamins. Cyanocobamide is also used to perform the Schilling test to check ability to absorb vitamin B
12
.



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Wikipedia

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