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Cyanoacetamide

2-Cyanoacetamide
Cyanoacetamide.svg
Names
IUPAC name
2-Cyanoacetamide
Other names
Malonamide nitrile
3-Nitrilopropionamide
Identifiers
107-91-5 YesY
3D model (Jmol) Interactive image
ChemSpider 7610
EC Number 203-531-8
UNII YBK38G2YXH YesY
Properties
C3H4N2O
Molar mass 84.08 g·mol−1
Density 1.163 g/cm3
Melting point 119 to 121 °C (246 to 250 °F; 392 to 394 K)
Boiling point 351.2 °C (664.2 °F; 624.3 K)
Hazards
R-phrases R8 R23/24/25 R36/38 R45
S-phrases S17 S45
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

2-Cyanoacetamide is a organic compound. It is an acetic amide with a nitrile functional group.

Cyanoacetamide is used in spectrofluorimetric methods to determine the activity of antihistamine H1 receptor antagonistic drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride.

2-Cyanoacetamide is prepared from chloroacetic acid via Kolbe nitrile synthesis followed by Fischer esterification and ester aminolysis.



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