Crimean–Congo hemorrhagic fever

Crimean-Congo hemorrhagic fever
Isolated male patient diagnosed with Crimean-Congo hemorrhagic fever, 1969
Classification and external resources
Specialty	Infectious disease
ICD-10	A98.0
ICD-9-CM	065.0
DiseasesDB	31969
MedlinePlus	article
eMedicine	830594/
[]

Crimean–Congo hemorrhagic fever
Virus classification
Group:	Group V ((−)ssRNA)
Order:	Unassigned
Family:	Bunyaviridae
Genus:	Nairovirus
Species:	Crimean-Congo hemorrhagic fever virus

Crimean–Congo hemorrhagic fever (CCHF) is a widespread tick-borne viral disease that is endemic in Africa, the Balkans, the Middle East and Asia. The virus is a member of the Bunyaviridae family of RNA viruses. It is a zoonotic disease carried by several domestic and wild animals. While clinical disease is rare in infected animals, it is severe in infected humans, with a mortality rate of 10-40%. Outbreaks of illness are usually attributable to Hyalomma tick bites or contact with infected animals or people. CCHF is one of several viral diseases identified by WHO as a likely cause of a future epidemic. They recommend it for urgent research and development.

Typically, after a 1–3 day incubation period following a tick bite (5–6 days after exposure to infected blood or tissues), flu-like symptoms appear, which may resolve after one week. In up to 75% of cases, however, signs of hemorrhage appear within 3–5 days of the onset of illness in case of bad containment of the first symptoms: mood instability, , mental confusion and throat petechiae; and soon after nosebleeds, vomiting, and black stools. The liver becomes swollen and painful. Disseminated intravascular coagulation may occur, as well as acute kidney failure, shock, and sometimes acute respiratory distress syndrome. Patients usually begin to show signs of recovery after 9–10 days from when symptoms presented. However 30% of the cases result in death by the end of the second week of illness.

The virus is a member of the genus Nairovirus, family Bunyaviridae.

...
Wikipedia