Coxsackie B virus | |
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Coxsackie B4 virus | |
Virus classification | |
Group: | Group IV ((+)ssRNA) |
Order: | unassigned |
Family: | Picornaviridae |
Genus: | Enterovirus |
Species: | Enterovirus B |
Subtype | |
Coxsackie B virus |
Coxsackie B virus
Coxsackie B is a group of six serotypes of Coxsackievirus, a pathogenic enterovirus, that trigger illness ranging from mild gastrointestinal distress to full-fledged pericarditis and myocarditis (Coxsackievirus-induced cardiomyopathy).
The virus has approximately 7400 base pair.
The various members of the Coxsackie B group were discovered almost entirely in the United States, appearing originally in Connecticut, Ohio, New York, and Kentucky, although a sixth member of the group has been found in the Philippines. However, all six serotypes have a global distribution and are a relatively common cause of gastrointestinal upset.
Symptoms of infection with viruses in the Coxsackie B grouping include fever, headache, sore throat, gastrointestinal distress, as well as chest and muscle pain. This presentation is known as pleurodynia or Bornholm disease in many areas. Sufferers of chest pain should see a doctor immediately—in some cases, viruses in the Coxsackie B family progress to myocarditis or pericarditis, which can result in permanent heart damage or death. Coxsackie B virus infection may also induce aseptic meningitis. As a group, they are the most common cause of unexpected sudden death, and may account for up to 50% of such cases. The incubation period for the Coxsackie B viruses ranges from 2 to 6 days, and illness may last for up to two weeks, but may resolve as quickly as two days. Infection usually occurs between the months of June and October in temperate Northern Hemisphere regions.