Corticosteroid-binding globulin

SERPINA6
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2VDX, 2VDY, 4BB2, 4C41, 4C49
Identifiers
Aliases	SERPINA6, CBG, serpin family A member 6
External IDs	OMIM: 122500 MGI: 88278 HomoloGene: 20417 GeneCards: SERPINA6
Gene ontology Molecular function • steroid binding • serine-type endopeptidase inhibitor activity • lipid binding Cellular component • extracellular region • extracellular exosome • extracellular space Biological process • transport • glucocorticoid metabolic process • negative regulation of endopeptidase activity Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	866	12401
Ensembl	n/a	ENSMUSG00000060807
UniProt	P08185	Q06770
RefSeq (mRNA)	NM_001756	NM_007618
RefSeq (protein)	NP_001747	NP_031644.1 NP_031644
Location (UCSC)	Chr 14: 94.3 – 94.32 Mb	Chr 12: 103.65 – 103.66 Mb
PubMed search

2VDX, 2VDY, 4BB2, 4C41, 4C49

866

12401

n/a

ENSMUSG00000060807

P08185

Q06770

NM_001756

NM_007618

NP_001747

NP_031644.1
NP_031644

Transcortin, also known as corticosteroid-binding globulin (CBG) or serpin A6 is a protein that in humans is encoded by the SERPINA6 gene. It is an alpha-globulin.

This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucocorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors (serpins) which have evolved by duplication events.

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Wikipedia