Complement factor B

CFB

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3HS0, 1DLE, 1Q0P, 1RRK, 1RS0, 1RTK, 2OK5, 2WIN, 2XWB, 2XWJ, 3HRZ

Identifiers

Aliases

CFB, Cfb, AI195813, AI255840, B, Bf, C2, Fb, H2-Bf, AHUS4, ARMD14, BFD, CFAB, CFBD, FBI12, GBG, PBF2, complement factor B

External IDs

MGI: 105975 HomoloGene: 1292 GeneCards: CFB

Genetically Related Diseases

age related macular degeneration

Gene ontology
Molecular function	• peptidase activity • serine-type peptidase activity • serine-type endopeptidase activity • hydrolase activity • complement binding
Cellular component	• extracellular region • plasma membrane • blood microparticle • extracellular exosome • extracellular space
Biological process	• complement activation • regulation of complement activation • proteolysis • immune system process • complement activation, alternative pathway • innate immune response
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


629


14962

Ensembl


n/a


ENSMUSG00000090231

UniProt


P00751


P04186

RefSeq (mRNA)


NM_001710


NM_001142706 NM_008198

RefSeq (protein)


NP_001701


NP_001136178 NP_032224

Location (UCSC)

Chr 6: 31.95 – 31.95 Mb

Chr 17: 34.86 – 34.86 Mb

PubMed search

3HS0, 1DLE, 1Q0P, 1RRK, 1RS0, 1RTK, 2OK5, 2WIN, 2XWB, 2XWJ, 3HRZ

n/a

NM_001142706
NM_008198

NP_001701

NP_001136178
NP_032224

...
Wikipedia