Complement component 5

C5
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1CFA, 1KJS, 1XWE, 3CU7, 3HQA, 3HQB, 3KLS, 3KM9, 3PRX, 3PVM, 4A5W, 4E0S, 4P39, 4UU9, 5I5K, 5HCE, 5HCC, 5HCD
Identifiers
Aliases	C5, C5D, C5a, C5b, CPAMD4, ECLZB, complement component 5, complement C5
External IDs	OMIM: 120900 MGI: 96031 HomoloGene: 20412 GeneCards: C5
Gene ontology Molecular function • chemokine activity • protein binding • endopeptidase inhibitor activity • receptor binding Cellular component • extracellular region • extracellular exosome • membrane attack complex • extracellular space Biological process • G-protein coupled receptor signaling pathway • cytolysis • complement activation, alternative pathway • immune system process • positive regulation of chemokine secretion • complement activation • response to stress • in utero embryonic development • positive regulation of angiogenesis • chemotaxis • cell surface receptor signaling pathway • activation of MAPK activity • complement activation, classical pathway • positive regulation of vascular endothelial growth factor production • inflammatory response • regulation of complement activation • negative regulation of macrophage chemotaxis • negative regulation of endopeptidase activity • innate immune response • cell chemotaxis Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	727	15139
Ensembl	ENSG00000106804	ENSMUSG00000026874
UniProt	P01031	P06684
RefSeq (mRNA)	NM_001735 NM_001317163 NM_001317164	NM_010406
RefSeq (protein)	NP_001304092 NP_001304093 NP_001726	NP_034536.2 NP_034536
Location (UCSC)	Chr 9: 120.95 – 121.05 Mb	Chr 2: 34.98 – 35.06 Mb
PubMed search

1CFA, 1KJS, 1XWE, 3CU7, 3HQA, 3HQB, 3KLS, 3KM9, 3PRX, 3PVM, 4A5W, 4E0S, 4P39, 4UU9, 5I5K, 5HCE, 5HCC, 5HCD

727

15139

ENSG00000106804

ENSMUSG00000026874

P01031

P06684

...
Wikipedia