Complement component 3

C3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4ONT, 1C3D, 1GHQ, 1W2S, 2A73, 2A74, 2GOX, 2I07, 2ICE, 2ICF, 2NOJ, 2QKI, 2WII, 2WIN, 2WY7, 2WY8, 2XQW, 2XWB, 2XWJ, 3D5R, 3D5S, 3G6J, 3L3O, 3L5N, 3NMS, 3OED, 3OHX, 3OXU, 3RJ3, 3T4A, 4HW5, 4HWJ, 4I6O, 4M76, 4ZH1, 5FOB, 5FO9, 5FO7, 5FO8, 5FOA
Identifiers
Aliases	C3, AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, HEL-S-62p, complement component 3, complement C3
External IDs	OMIM: 120700 MGI: 88227 HomoloGene: 68031 GeneCards: C3
Gene ontology Molecular function • C5L2 anaphylatoxin chemotactic receptor binding • protein binding • endopeptidase inhibitor activity • receptor binding • serine-type endopeptidase activity Cellular component • blood microparticle • plasma membrane • • extracellular region • extracellular exosome Biological process • G-protein coupled receptor signaling pathway • positive regulation of phagocytosis • positive regulation of protein phosphorylation • complement activation, alternative pathway • lipid metabolic process • immune system process • complement activation • positive regulation of lipid storage • positive regulation of type IIa hypersensitivity • fatty acid metabolic process • positive regulation of angiogenesis • positive regulation of G-protein coupled receptor protein signaling pathway • positive regulation of apoptotic cell clearance • immune response • complement activation, classical pathway • regulation of immune response • positive regulation of activation of membrane attack complex • positive regulation of vascular endothelial growth factor production • inflammatory response • positive regulation of glucose transport • regulation of complement activation • signal transduction • negative regulation of endopeptidase activity • regulation of triglyceride biosynthetic process • proteolysis • innate immune response Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	718	12266
Ensembl	ENSG00000125730	ENSMUSG00000024164
UniProt	P01024	P01027
RefSeq (mRNA)	NM_000064	NM_009778
RefSeq (protein)	NP_000055	NP_033908.2 NP_033908
Location (UCSC)	Chr 19: 6.68 – 6.73 Mb	Chr 17: 57.2 – 57.23 Mb
PubMed search

4ONT, 1C3D, 1GHQ, 1W2S, 2A73, 2A74, 2GOX, 2I07, 2ICE, 2ICF, 2NOJ, 2QKI, 2WII, 2WIN, 2WY7, 2WY8, 2XQW, 2XWB, 2XWJ, 3D5R, 3D5S, 3G6J, 3L3O, 3L5N, 3NMS, 3OED, 3OHX, 3OXU, 3RJ3, 3T4A, 4HW5, 4HWJ, 4I6O, 4M76, 4ZH1, 5FOB, 5FO9, 5FO7, 5FO8, 5FOA

...
Wikipedia