Complement Factor I

CFI
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2XRC
Identifiers
Aliases	CFI, AHUS3, ARMD13, C3BINA, C3b-INA, FI, IF, KAF, complement factor I
External IDs	MGI: 105937 HomoloGene: 171 GeneCards: CFI
Gene ontology Molecular function • peptidase activity • hydrolase activity • serine-type peptidase activity • metal ion binding • serine-type endopeptidase activity • scavenger receptor activity • protein binding Cellular component • extracellular exosome • membrane • extracellular region • extracellular space Biological process • complement activation, classical pathway • regulation of complement activation • receptor-mediated endocytosis • proteolysis • immune system process • innate immune response Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3426	12630
Ensembl	ENSG00000205403	ENSMUSG00000058952
UniProt	P05156 Q8WW88	Q61129
RefSeq (mRNA)	NM_000204 NM_001318057 NM_001331035	NM_007686 NM_001329552
RefSeq (protein)	NP_000195 NP_001304986 NP_001317964 NP_001304986.1	NP_031712.2 NP_001316481 NP_031712
Location (UCSC)	Chr 4: 109.74 – 109.8 Mb	Chr 3: 129.84 – 129.88 Mb
PubMed search

2XRC

3426

12630

ENSG00000205403

ENSMUSG00000058952

P05156
Q8WW88

Q61129

NM_000204
NM_001318057
NM_001331035

NM_007686
NM_001329552

NP_000195
NP_001304986
NP_001317964
NP_001304986.1

NP_031712.2
NP_001316481
NP_031712

Complement factor I, also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene.

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Wikipedia