Clare Peploe (born 1942) is a British screenwriter, producer and film director.
Peploe was born in Tanzania but grew up in England and Italy, and had a brother named Mark Peploe. At an early age, Peploe developed an interest in cinema and art. She went on to study at the Sorbonne and University of Perugia. Peploe debuted as a director with the short film, Couples and Robbers (1981) which received nominations for the Oscars and BAFTA respectively. Her third feature, The Triumph of Love competed at the 2001 Venice Film Festival and was nominated for the Golden Lion Award. As a screenwriter, Peploe is recognised as a frequent collaborator with her husband, Bernardo Bertolucci. She is also credited with co-writing the 1970 cult film, Zabriskie Point with Michelangelo Antonioni and others.