The City of Carlisle (/kɑːrˈlaɪl/ or local /ˈkɑːrlaɪl/) is a local government district of Cumbria, England, with the status of a city and non-metropolitan district. It is named after its largest settlement, Carlisle, but covers a far larger area which includes the towns of Brampton and Longtown, as well as outlying villages including Dalston, Scotby and Wetheral. The city has a population of 107,524. and an area of 1,039.97 square kilometres (402 sq mi), making it the largest city in England by area (although the majority of its territory is not urbanised, but rural).

The current city boundaries were set as part of the provisions of the Local Government Act 1972, and cover an amalgamation of two former local government districts—the City and County Borough of Carlisle and the Border Rural District of Cumberland. The City of Carlisle shares a border with Scotland (to the north), and is bounded on the southwest by the borough of Allerdale, and on the south by the district of Eden. The county of Northumberland is to the east.