Cisco Independent School District is a public school district based in Cisco, Texas (USA).
Located in Eastland County, a very small portion of the district extends into Callahan County.
Cisco Junior College was originally part of the district until 1956, when it became a stand-alone entity.
Rupert N. Richardson, a Texas historian who was later the president of Hardin-Simmons University in Abilene, was principal at Cisco High School from 1915-1916.
In 2009, the school district was rated "recognized" by the Texas Education Agency.