Cincinnati (/ˌsɪnsᵻˈnæti/ SIN-si-NAT-ee) is a city in the U.S. state of Ohio that serves as county seat of Hamilton County. Settled in 1788, the city is located on the north side of the confluence of the Licking with the Ohio River. With a population of 298,550, Cincinnati is the third-largest city in Ohio and the 65th-largest city in the United States. Its metropolitan statistical area is the 28th-largest in the United States and the largest centered in Ohio. The city is also part of the larger Cincinnati–Middletown–Wilmington combined statistical area, which had a population of 2,172,191 in the 2010 census.

In the early 19th century, Cincinnati was an American boomtown in the heart of the country; it rivaled the larger coastal cities in size and wealth. Throughout much of the 19th century, it was listed among the top 10 U.S. cities by population, surpassed only by New Orleans and the older, established settlements of the Eastern Seaboard; at one point holding the position of America's sixth-largest city for a period spanning consecutive census reports from 1840 until 1860. It was by far the largest city in the west. Because it is the first major American city founded after the American Revolution as well as the first major inland city in the country, Cincinnati is sometimes thought of as the first purely "American" city.

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