Chorionic gonadotropin beta

CGB3

Available structures

Human UniProt search: PDBe RCSB

List of PDB id codes
1HCN, 1HRP, 1QFW,%%s1QFW, 1HCN, 1HRP

Identifiers

Aliases

CGB3, CGB5, CGB7, CGB8, hCGB, CGB, Chorionic gonadotropin beta, chorionic gonadotropin beta subunit 3, Choriogonadotropin subunit beta

External IDs

HomoloGene: 37338 GeneCards: CGB3

Gene ontology
Molecular function	• hormone activity
Cellular component	• extracellular region
Biological process	• peptide hormone processing • apoptotic process • cellular protein metabolic process • signal transduction • female gamete generation • cell-cell signaling • regulation of transcription from RNA polymerase II promoter
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


1082


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Ensembl


ENSG00000104827


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UniProt


P01233 P0DN86


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RefSeq (mRNA)


NM_000737


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RefSeq (protein)

NP_000728.1 NP_149032.1 NP_149133.1 NP_149439.1 NP_149439
NP_000728 NP_149032


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Location (UCSC)

Chr 19: 49.02 – 49.02 Mb

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PubMed search

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1HCN, 1HRP, 1QFW,%%s1QFW, 1HCN, 1HRP

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Choriogonadotropin subunit beta (CG-beta) also known as chorionic gonadotrophin chain beta is a protein that in humans is encoded by the CGB gene.

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and a unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.

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Wikipedia