The Chemins de fer de Paris à Orléans et du Midi, often abbreviated to PO-Midi, was an early French railway company. It was formed in 1934 following the merging of the Chemin de fer de Paris à Orléans and the Chemins de fer du Midi.
In 1937 it was nationalised to become part of the Société Nationale des Chemins de fer Français (SNCF).