Coordinates: 29°42′39″N 95°16′38″W / 29.7107°N 95.2771°W
Charles H. Milby High School is a public secondary school at 1601 Broadway in the East End, Houston, Texas, with a ZIP code of 77012. Milby, which serves grades 9 through 12, is a part of the Houston Independent School District.
Milby is located inside the 610 Loop in southeast Houston. Milby contains Houston ISD's Science Institute Magnet Program. As of 2014, the school's principal administrator is Roy de la Garza.
In 2014, J. Howard Johnston and Ronald Williamson described Milby's neighborhood as "one of the most impoverished parts of Houston".
Milby began its life in March 1926, replacing the former Harrisburg High School, which was located several blocks south of Milby. Thirteen teachers and 212 students formed Milby's initial population. The $180,000 United States dollar campus had and still has a Romanesque exterior. Since its opening, Milby had various expansions and renovations. Originally a predominately non-Hispanic White school, Milby became mostly Hispanic as the population of the East End area increased.
Prior to the 1970s, desegregated Milby admitted White and Hispanic students while it did not admit Black students.
Milby High School was one of the locations where the movie My Best Friend Is a Vampire was filmed in 1986. The school was renamed "Milton High School" in the movie. Many interior scenes, including scenes of the main character in his bedroom, were filmed inside the school and the school's exterior was used in the movie as well. Students at Milby were extras in many scenes, as the filming took place during school hours. After the movie was completed, the sign on the exterior of the school that had been in disrepair was replaced with a new one by the production company.