Cellulite

Cellulite
The dimpled appearance of cellulite
Classification and external resources
Specialty	Plastic surgery
MedlinePlus	002033
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Cellulite (also known as adiposis edematosa, dermopanniculosis deformans, status protrusus cutis, gynoid lipodystrophy, and orange peel syndrome) is the herniation of subcutaneous fat within fibrous connective tissue that manifests topographically as skin dimpling and nodularity, often on the pelvic region (specifically the ), lower limbs, and abdomen. Cellulite is a secondary sex characteristic occurring in most postpubescent females. A review gives a prevalence of 85%-98% of women, indicating that it is physiologic rather than pathologic. It can result from a complex combination of factors ranging from hormones to heredity.

The causes of cellulite include changes in metabolism, physiology, diet and exercise habits, sex-specific dimorphic skin architecture, alteration of connective tissue structure, hormonal factors, genetic factors, the microcirculatory system, the extracellular matrix, and subtle inflammatory alterations.

Hormones play a dominant role in the formation of cellulite. Estrogen may be the important hormone in the development of cellulite. However, there has been no reliable clinical evidence to support such a claim. Other hormones, including insulin, the catecholamines adrenaline and noradrenaline, thyroid hormones, and prolactin, are all believed to participate in the development of cellulite.

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