Cathepsin S

CTSS
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1GLO, 1MS6, 1NPZ, 1NQC, 2C0Y, 2F1G, 2FQ9, 2FRA, 2FRQ, 2FT2, 2FUD, 2FYE, 2G6D, 2G7Y, 2H7J, 2HH5, 2HHN, 2HXZ, 2OP3, 2R9M, 2R9N, 2R9O, 3IEJ, 3KWN, 3MPE, 3MPF, 3N3G, 3N4C, 3OVX, 4P6E, 4P6G
Identifiers
Aliases	CTSS, entrez:1520, cathepsin S
External IDs	MGI: 107341 HomoloGene: 20867 GeneCards: CTSS
Gene ontology Molecular function • fibronectin binding • cysteine-type peptidase activity • collagen binding • peptidase activity • cysteine-type endopeptidase activity • laminin binding • hydrolase activity • proteoglycan binding • serine-type endopeptidase activity Cellular component • intracellular membrane-bounded organelle • extracellular region • endolysosome lumen • lysosomal lumen • lysosome • extracellular space • tertiary granule lumen • ficolin-1-rich granule lumen Biological process • positive regulation of cation channel activity • antigen processing and presentation • adaptive immune response • antigen processing and presentation of exogenous peptide antigen via MHC class II • protein processing • extracellular matrix disassembly • proteolysis • toll-like receptor signaling pathway • antigen processing and presentation of peptide antigen • immune response • cellular response to thyroid hormone stimulus • collagen catabolic process • proteolysis involved in cellular protein catabolic process • basement membrane disassembly • response to acidic pH • neutrophil degranulation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1520	13040
Ensembl	ENSG00000163131	ENSMUSG00000038642
UniProt	P25774	O70370
RefSeq (mRNA)	NM_004079 NM_001199739	NM_001267695 NM_021281
RefSeq (protein)	NP_001186668 NP_004070	NP_067256.4 NP_001254624 NP_067256
Location (UCSC)	Chr 1: 150.73 – 150.77 Mb	Chr 3: 95.53 – 95.56 Mb
PubMed search

1GLO, 1MS6, 1NPZ, 1NQC, 2C0Y, 2F1G, 2FQ9, 2FRA, 2FRQ, 2FT2, 2FUD, 2FYE, 2G6D, 2G7Y, 2H7J, 2HH5, 2HHN, 2HXZ, 2OP3, 2R9M, 2R9N, 2R9O, 3IEJ, 3KWN, 3MPE, 3MPF, 3N3G, 3N4C, 3OVX, 4P6E, 4P6G

...
Wikipedia