Cathepsin B

CTSB

PDB 1csb EBI.jpg

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3PBH, 1CSB, 1GMY, 1HUC, 1PBH, 2IPP, 2PBH, 3AI8, 3CBJ, 3CBK, 3K9M

Identifiers

CTSB, APPS, CPSB, cathepsin B

External IDs

OMIM: 116810 MGI: 88561 HomoloGene: 37550 GeneCards: CTSB

Gene ontology
Molecular function	• cysteine-type peptidase activity • collagen binding • peptidase activity • protein binding • cysteine-type endopeptidase activity • hydrolase activity • proteoglycan binding • serine-type endopeptidase activity
Cellular component	• intracellular membrane-bounded organelle • melanosome • intracellular • extracellular region • endolysosome lumen • nucleolus • mitochondrion • lysosome • extracellular exosome • perinuclear region of cytoplasm • extracellular space • ficolin-1-rich granule lumen
Biological process	• regulation of apoptotic process • epithelial cell differentiation • proteolysis • toll-like receptor signaling pathway • decidualization • cellular response to thyroid hormone stimulus • collagen catabolic process • viral entry into host cell • regulation of catalytic activity • proteolysis involved in cellular protein catabolic process • neutrophil degranulation
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE CTSB 213274 s at fs.png

PBB GE CTSB 200838 at fs.png

PBB GE CTSB 200839 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


1508


13030


ENSG00000164733


ENSMUSG00000021939


P07858


P10605

RefSeq (mRNA)

NM_001908 NM_147780 NM_147781 NM_147782 NM_147783
NM_001317237


NM_007798

RefSeq (protein)

NP_001304166 NP_001899 NP_680090 NP_680091 NP_680092
NP_680093


NP_031824.1 NP_031824

Location (UCSC)

Chr 8: 11.84 – 11.87 Mb

Chr 14: 63.12 – 63.15 Mb

PubMed search

3PBH, 1CSB, 1GMY, 1HUC, 1PBH, 2IPP, 2PBH, 3AI8, 3CBJ, 3CBK, 3K9M

ENSG00000164733

ENSMUSG00000021939

NP_031824.1
NP_031824

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Wikipedia

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