CatSper4

CATSPER4
Identifiers
Aliases	CATSPER4, CatSper4, cation channel sperm associated 4
External IDs	MGI: 3043288 HomoloGene: 18638 GeneCards: CATSPER4
Gene ontology Molecular function • voltage-gated calcium channel activity • calcium activated cation channel activity • calcium channel activity • voltage-gated ion channel activity • ion channel activity • NAADP-sensitive calcium-release channel activity Cellular component • integral component of membrane • CatSper complex • cell projection • membrane • plasma membrane • cilium • sperm principal piece • acrosomal vesicle • motile cilium Biological process • flagellated sperm motility • cell differentiation • membrane depolarization during action potential • sodium ion transport • regulation of ion transmembrane transport • ion transport • multicellular organism development • calcium ion transmembrane transport • transmembrane transport • spermatogenesis • sperm-egg recognition • transport • sperm capacitation • response to progesterone • release of sequestered calcium ion into cytosol • calcium ion transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	378807	329954
Ensembl	ENSG00000188782	ENSMUSG00000048003
UniProt	Q7RTX7	Q8BVN3
RefSeq (mRNA)	NM_198137	NM_001130030 NM_177866
RefSeq (protein)	NP_937770	NP_001123502.1 NP_808534.1 NP_001123502 NP_808534
Location (UCSC)	Chr 1: 26.19 – 26.2 Mb	Chr 4: 134.21 – 134.23 Mb
PubMed search

378807

329954

ENSG00000188782

ENSMUSG00000048003

Q7RTX7

Q8BVN3

NM_198137

NM_001130030
NM_177866

NP_937770

NP_001123502.1
NP_808534.1
NP_001123502
NP_808534

CatSper4, is a protein which in humans is encoded by the CATSPER4 gene. CatSper1 is a member of the cation channels of sperm family of protein. The four proteins in this family together form a Ca²⁺-permeant ion channel specific essential for the correct function of sperm cells.

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Wikipedia