CatSper3

CATSPER3
Identifiers
Aliases	CATSPER3, CACRC, CatSper3, cation channel sperm associated 3
External IDs	MGI: 1924106 HomoloGene: 12658 GeneCards: CATSPER3
Targeted by Drug
alprostadil, dinoprostone, progesterone, mibefradil
Gene ontology Molecular function • voltage-gated calcium channel activity • calcium channel activity • voltage-gated ion channel activity • ion channel activity • cation channel activity Cellular component • integral component of membrane • CatSper complex • cell projection • membrane • plasma membrane • cilium • acrosomal vesicle • endoplasmic reticulum • motile cilium Biological process • flagellated sperm motility • cell differentiation • membrane depolarization during action potential • sodium ion transport • regulation of ion transmembrane transport • ion transport • multicellular organism development • ion transmembrane transport • calcium ion transmembrane transport • transmembrane transport • spermatogenesis • sperm-egg recognition • transport • sperm capacitation • calcium ion transport • response to progesterone Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	347732	76856
Ensembl	ENSG00000152705	ENSMUSG00000021499
UniProt	Q86XQ3	Q80W99
RefSeq (mRNA)	NM_178019	NM_001252487 NM_001252488 NM_029772
RefSeq (protein)	NP_821138	NP_001239416.1 NP_084048.1
Location (UCSC)	Chr 5: 134.97 – 135.01 Mb	Chr 13: 55.78 – 55.81 Mb
PubMed search

347732

76856

ENSG00000152705

ENSMUSG00000021499

Q86XQ3

Q80W99

NM_178019

NM_001252487
NM_001252488
NM_029772

NP_821138

NP_001239416.1
NP_084048.1

CatSper3, is a protein which in humans is encoded by the CATSPER3 gene. CatSper3 is a member of the cation channels of sperm family of proteins. The four proteins in this family together form a Ca²⁺-permeant ion channel specific essential for the correct function of sperm cells.

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Wikipedia