Caspase-9

CASP9

Protein CASP9 PDB 1jxq.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4RHW, 1JXQ, 1NW9, 2AR9, 3D9T, 3V3K, 3YGS

Identifiers

CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56, caspase 9

External IDs

OMIM: 602234 MGI: 1277950 HomoloGene: 31024 GeneCards: CASP9

Gene ontology
Molecular function	• cysteine-type peptidase activity • SH3 domain binding • peptidase activity • protein binding • enzyme activator activity • cysteine-type endopeptidase activity • hydrolase activity • protein kinase binding • cysteine-type endopeptidase activity involved in execution phase of apoptosis
Cellular component	• cytoplasm • cytosol • mitochondrion • apoptosome • nucleus
Biological process	• regulation of apoptotic process • response to estradiol • response to organic cyclic compound • signal transduction in response to DNA damage • cellular response to UV • response to antibiotic • cellular response to organic cyclic compound • aging • platelet formation • glial cell apoptotic process • cellular response to dexamethasone stimulus • proteolysis • cellular response to DNA damage stimulus • response to lipopolysaccharide • positive regulation of neuron apoptotic process • activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c • intrinsic apoptotic signaling pathway in response to DNA damage • extrinsic apoptotic signaling pathway in absence of ligand • positive regulation of apoptotic process • regulation of response to DNA damage stimulus • response to cobalt ion • activation of cysteine-type endopeptidase activity involved in apoptotic process • response to UV • apoptotic process • execution phase of apoptosis
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE CASP9 210775 x at fs.png

PBB GE CASP9 203984 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


842


12371


ENSG00000132906


ENSMUSG00000028914


P55211


Q8C3Q9

RefSeq (mRNA)


NM_001229 NM_001278054 NM_032996


NM_001277932 NM_015733

RefSeq (protein)


NP_001220 NP_001264983 NP_127463


NP_056548.2 NP_001264861 NP_056548

Location (UCSC)

Chr 1: 15.49 – 15.53 Mb

Chr 4: 141.79 – 141.82 Mb

PubMed search

4RHW, 1JXQ, 1NW9, 2AR9, 3D9T, 3V3K, 3YGS

ENSG00000132906

ENSMUSG00000028914

NM_001229
NM_001278054
NM_032996

NM_001277932
NM_015733

NP_001220
NP_001264983
NP_127463

NP_056548.2
NP_001264861
NP_056548

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Wikipedia

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