Candida auris

Candida auris
Scientific classification
Kingdom:	Fungi
Division:	Ascomycota
Class:	Saccharomycetes
Order:	Saccharomycetales
Family:	Debaryomycetaceae
Genus:	Candida
Species:	C. auris
Binomial name
Candida auris
Type strain
DSM 21092

Candida auris is a species of ascomycetous fungus that grows as yeast. It was first described in 2009. It is one of the few species of the Candida genus that cause candidiasis in humans. Candidiasis is often acquired in hospitals by patients with weakened immune systems. Besides candidiasis, C. auris can cause invasive candidiasis in which the blood (fungemia), the central nervous system, kidneys, liver, bones, muscles, joints, spleen, or eyes are infected. C. auris has recently attracted increased clinical attention because of its multidrug resistance. Treatment is also complicated because C. auris is easily misidentified as other Candida species. A brief outline of its clinical relevance as of 2016, understandable by general audiences, was published by the Center for Infectious Disease Research and Policy at the University of Minnesota. The name Candida auris comes from the Latin word for ear, auris, under the genus Candida. It was named a "catastrophic threat" by Dr. Anne Schuchat.

Several draft genomes from whole genome sequencing have been published. The C. auris genome was found to encode several genes for the ABC transporter family and major facilitator superfamily which helps to explain its multidrug resistance. It's genome also encodes virulence-related gene families such as lipases, oligopeptide transporters, mannosyl transferases and transcription factors which facilitate colonization, invasion and iron acquisition. An additional factor contributing to antifungal resistance is the presence of a set of genes known to be involved in biofilm formation.

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