Campuzano Polanco was an elite family from the colony of Santo Domingo (today Dominican Republic) with origins in Santiago de los Caballeros. Unlike any other family from the colonial era of the Hispaniola, their members and descendants went on to occupy the highest political, military and ecclesiastical positions, not only locally and outside the Island, but also in the metropolis of Spain. Their list of merits extends for over 300 years since the beginning and until the end of the colony.
Pedro Perez Polanco (c.1640-1710) was a captain of the military bands of the "cincuentenas" (bands of 50 cavalry lancers ) from the northern part of the island of the Hispaniola who lead successful military campaigns against the English invasion of Penn and Venables in 1655 and against the French in the Battle of the Limonade in 1691. Along with other captains such as Luis Lopez Tirado, Antonio Pichardo Vinuesa, Antonio Miniel, Jose Morel de Santa Cruz, Francisco del Monte and others, Polanco constituted the military and political elite of Santiago de los Caballeros and the North coast.
Perez Polanco was also Mayor of Santiago de los Caballeros and well off hatero (herder), rancher and sugar mill owner. His father, Garcia Perez Polanco (c.1620- 1656), had also been a captain of the northern military bands defending the northern coast and towns against the buccaneers and the filibusters from the Tortuga Island. His mother was Ines Martinez Mejia.
His grandfather, Pedro Polanco de Henao (c.1590-1680), was Mayor of the town of Concepcion de La Vega in 1623 and was married to Ana Minaya Alconchel. His greatgrandparents Garcia Perez Polanco (c.1550) and Apolinaria de Henao y Almeida Casasola descended from nobles and the earliest settlers of Santiago de los Caballeros, La Vega and Cotui, three of the oldest European settlements in the American continent. Garcia Perez Polanco was also Mayor of La Vega around 1575.