Camargo is a municipality in the Mexican state of Tamaulipas. It is located on the US border, across from Rio Grande City, Texas. It has an official population of 14,933 inhabitants (2010 census) and an international bridge. The municipal seat is Ciudad Camargo, with a population of 7,984. The municipality is connected to Rio Grande City, Texas via the Rio Grande City-Camargo International Bridge.
The first settlement to be founded on the Lower Río Grande was that of Nuestra Señora de Santa Ana de Camargo. It was founded on March 5, 1749, with the dedication to Señora Santa Ana by captain Don Blas María de la Garza Falcón at the eastern edge of the San Juan River near its confluence with the Río Grande. The foundation had 85 families – a total of 531 persons. Most of the settlers for this township came from Cerralvo, Cadereyta, Monterrey and surrounding townships.
After establishing other towns in the interior of Mexico between Querétaro and the Gulf coast, Escandon arrived at Camargo on March 3, 1749. At the location called, "Paso del Azucar" on the Rio Grande, about two leagues southeast of the present site of Camargo, he met Captain Blas Maria de la Garza Falcón who already had been encamped their with forty other families and some soldiers. In the group led by Captain Blas Maria de la Garza Falcon were Miguel de la Garza Falcon, his brother, and Nicolas de los Santos Coy, father-in-law of Captain Falcon and ex-alcalde of nearby Cerralvo Municipality in Nuevo León.