"Call Me When You're Sober" is a song by American rock band Evanescence. It was written by Amy Lee and Terry Balsamo, produced by Dave Fortman, and included on their second studio album The Open Door. The track was leaked to radio on July 30, 2006, allowing several radio stations to play the track early without it being released as a CD single. It became available for digital download on September 4, and was officially announced and released as a single on September 25, 2006, through the band's record label Wind-up Records. Lee confirmed that the song was written about her ex-boyfriend Shaun Morgan, lead singer of the band Seether.

The song received generally positive reviews from music critics who praised the instrumentation, the rock sound, and Lee's vocals which were described as "strong". "Call Me When You're Sober" peaked at number 10 on the Billboard Hot 100, number 4 on the Billboard Alternative Songs chart, and within the top 20 on several more charts internationally. The single was certified Gold by the Australian Recording Industry Association (ARIA) in 2006 and platinum by the Recording Industry Association of America (RIAA).

The accompanying music video, directed by Marc Webb and filmed in Hollywood, Los Angeles was based on the fairy tale Little Red Riding Hood. It portrays Lee and her ex-lover, played by the British actor Oliver Goodwill. Segments of the band performing the song and Lee singing with wolves are also shown during the video. "Call Me When You're Sober" was part of the set list during two of Evanescence's worldwide tours, The Open Door Tour (2006–07) and the Evanescence Tour (2011–12). It has been covered by American Idol contestant Gina Glocksen and used in the video game Rock Band.

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