Calico is an unincorporated community in Pitt County, in the U.S. state of North Carolina.
A post office called Calico was established in 1882, and remained in operation until 1902. Calico was so named on account of the community being a trading point where calico was sold.
Coordinates: 35°25′07″N 77°15′17″W / 35.41861°N 77.25472°W