Cairo Unified School District 1

Cairo Unified School District 1 is a unified school district located in the southern Illinois' Alexander County, and more specifically in the county seat of Alexander County, Cairo, Illinois; its location in the southernmost city in Illinois implies that it is also the southernmost school district in the state. It is composed of two schools: Cairo Elementary School, which educates primary to fifth graders; and Cairo Junior and Senior High School, which encompasses grades six through twelve.

During the 2016 school year, the district's enrollment for all grades was 476.

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