CYP3A5

CYP3A5
Identifiers
Aliases	CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3, cytochrome P450 family 3 subfamily A member 5
External IDs	MGI: 2449818 HomoloGene: 133568 GeneCards: CYP3A5
Gene ontology Molecular function • iron ion binding • oxidoreductase activity • oxygen binding • aromatase activity • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen • heme binding • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen • metal ion binding • monooxygenase activity • estrogen 16-alpha-hydroxylase activity Cellular component • organelle membrane • endoplasmic reticulum membrane • intracellular membrane-bounded organelle • endoplasmic reticulum • membrane Biological process • drug catabolic process • xenobiotic metabolic process • oxidation-reduction process • alkaloid catabolic process • oxidative demethylation • lipid hydroxylation • steroid metabolic process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1577	337924
Ensembl	ENSG00000106258	ENSMUSG00000054417
UniProt	P20815	Q9EQW4
RefSeq (mRNA)	NM_000777 NM_001190484 NM_001291829 NM_001291830	NM_177380
RefSeq (protein)	NP_000768 NP_001177413 NP_001278758 NP_001278759	NP_796354
Location (UCSC)	Chr 7: 99.65 – 99.68 Mb	Chr 5: 145.77 – 145.81 Mb
PubMed search

1577

337924

ENSG00000106258

ENSMUSG00000054417

P20815

Q9EQW4

NM_000777
NM_001190484
NM_001291829
NM_001291830

NM_177380

NP_000768
NP_001177413
NP_001278758
NP_001278759

NP_796354

Cytochrome P450 3A5 is a protein that in humans is encoded by the CYP3A5 gene.

CYP3A5 encodes a member of the cytochrome P450 superfamily of enzymes. Like most of the Cytochrome P450, the CYP3A5 is expressed in the prostate and the liver. It is also expressed in epithelium of the small intestine and large intestine for uptake and in small amounts in the bile duct, nasal mucosa, kidney, adrenal cortex, epithelium of the gastric mucosa with intestinal metaplasia, gallbladder, intercalated ducts of the pancreas, chief cells of the parathyroid and the corpus luteum of the ovary (at protein level).

...
Wikipedia