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CYP3A

CYP3A
Identifiers
Aliases cytochrome P450family 3subfamily ACYP3
External IDs GeneCards: [1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000775

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RefSeq (protein)

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Location (UCSC) n/a n/a
PubMed search n/a

NM_000775

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Cytochrome P450, family 3, subfamily A, also known as CYP3A, is a human gene.

The CYP3A locus includes all the known members of the 3A subfamily of the superfamily of genes. These genes encode monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The CYP3A cluster consists of four genes:

The region also contains two pseudogenes:

as well as several extra exons which may or may not be included in transcripts produced from this region. Previously another CYP3A member, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4.



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Wikipedia

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