CXCL7

PPBP
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 1TVX, 1F9P, 1NAP
Identifiers
Aliases	PPBP, B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1, pro-platelet basic protein
External IDs	HomoloGene: 136759 GeneCards: PPBP
Gene ontology Molecular function • growth factor activity • cytokine activity • glucose transmembrane transporter activity • CXCR chemokine receptor binding • chemokine activity Cellular component • platelet alpha granule lumen • extracellular region • extracellular space • tertiary granule lumen • platelet alpha granule Biological process • leukocyte migration involved in inflammatory response • response to lipopolysaccharide • regulation of cell proliferation • G-protein coupled receptor signaling pathway • glucose transport • chemotaxis • positive regulation of cell division • platelet degranulation • defense response to bacterium • inflammatory response • immune response • chemokine-mediated signaling pathway • neutrophil chemotaxis • glucose transmembrane transport • defense response • neutrophil degranulation • positive regulation of neutrophil chemotaxis • killing of cells of other organism • antimicrobial humoral immune response mediated by antimicrobial peptide Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5473	n/a
Ensembl	ENSG00000163736	n/a
UniProt	P02775	n/a
RefSeq (mRNA)	NM_002704	n/a
RefSeq (protein)	NP_002695	n/a
Location (UCSC)	Chr 4: 73.99 – 73.99 Mb	n/a
PubMed search		n/a

1TVX, 1F9P, 1NAP

5473

n/a

ENSG00000163736

n/a

P02775

n/a

NM_002704

n/a

NP_002695

n/a

Chemokine (C-X-C motif) ligand 7 (CXCL7) is a human gene.

The encoded protein, Chemokine (C-X-C motif) ligand is a small cytokine belonging to the CXC chemokine family. It is an isoform of Beta-Thromboglobulin or Pro-Platelet basic protein (PPBP).

It is a protein that is released in large amounts from platelets following their activation. It stimulates various processes including mitogenesis, synthesis of extracellular matrix, glucose metabolism and synthesis of plasminogen activator.

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Wikipedia