CTNS (gene)

CTNS
Identifiers
Aliases	CTNS, CTNS-LSB, PQLC4, cystinosin, lysosomal cystine transporter
External IDs	MGI: 1932872 HomoloGene: 3625 GeneCards: CTNS
Gene ontology Molecular function • L-cystine transmembrane transporter activity Cellular component • late endosome • intermediate filament cytoskeleton • integral component of membrane • intracellular membrane-bounded organelle • early endosome • membrane • melanosome • lysosome • plasma membrane • extracellular exosome • lysosomal membrane Biological process • cognition • melanin biosynthetic process • transmembrane transport • glutathione metabolic process • visual learning • long-term memory • brain development • lens development in camera-type eye • adult walking behavior • ion transport • ATP metabolic process • cellular amino acid metabolic process • grooming behavior • L-cystine transport • transport • negative regulation of hydrogen peroxide biosynthetic process • positive regulation of mitochondrial membrane potential • negative regulation of reactive oxygen species biosynthetic process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1497	83429
Ensembl	ENSG00000040531	ENSMUSG00000005949
UniProt	O60931	P57757
RefSeq (mRNA)	NM_001031681 NM_004937	NM_031251
RefSeq (protein)	NP_001026851 NP_004928	NP_112541
Location (UCSC)	Chr 17: 3.64 – 3.66 Mb	Chr 11: 73.18 – 73.2 Mb
PubMed search

1497

83429

ENSG00000040531

ENSMUSG00000005949

O60931

P57757

NM_001031681
NM_004937

NM_031251

NP_001026851
NP_004928

NP_112541

Cystinosin is a protein that in humans is encoded by the CTNS gene.

...
Wikipedia