CRYAB

CRYAB
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2KLR, 2N0K, 2WJ7, 2Y1Y, 2Y1Z, 2Y22, 2YGD, 3L1G, 3SGM, 3SGN, 3SGO, 3SGP, 3SGR, 3SGS, 4M5S, 4M5T, 3J07
Identifiers
Aliases	CRYAB, CMD1II, CRYA2, CTPP2, CTRCT16, HEL-S-101, HSPB5, MFM2, crystallin alpha B
External IDs	MGI: 88516 HomoloGene: 68209 GeneCards: CRYAB
Gene ontology Molecular function • protein homodimerization activity • microtubule binding • unfolded protein binding • metal ion binding • cytoskeletal protein binding • protein binding • structural constituent of eye lens • identical protein binding Cellular component • cytoplasm • Golgi apparatus • I band • microtubule cytoskeleton • nucleoplasm • cell surface • actin filament bundle • extracellular exosome • nucleus • cardiac myofibril • perikaryon • dendritic spine • synaptic membrane • synapse • M band • postsynaptic density of dendrite • axon Biological process • negative regulation of intracellular transport • response to estradiol • muscle contraction • regulation of cell death • aging • negative regulation of apoptotic process • microtubule polymerization or depolymerization • protein folding • stress-activated MAPK cascade • negative regulation of cell growth • cellular response to gamma radiation • regulation of cellular response to heat • negative regulation of reactive oxygen species metabolic process • protein homooligomerization • response to hydrogen peroxide Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1410	12955
Ensembl	ENSG00000109846	ENSMUSG00000032060
UniProt	P02511	P23927
RefSeq (mRNA)	NM_001289807 NM_001289808 NM_001885 NM_001330379	NM_001289782 NM_001289784 NM_001289785 NM_009964
RefSeq (protein)	NP_001276736 NP_001276737 NP_001317308 NP_001876	NP_001276711 NP_001276713 NP_001276714 NP_034094
Location (UCSC)	Chr 11: 111.91 – 111.92 Mb	Chr 9: 50.75 – 50.76 Mb
PubMed search

2KLR, 2N0K, 2WJ7, 2Y1Y, 2Y1Z, 2Y22, 2YGD, 3L1G, 3SGM, 3SGN, 3SGO, 3SGP, 3SGR, 3SGS, 4M5S, 4M5T, 3J07

1410

12955

ENSG00000109846

ENSMUSG00000032060

P02511

P23927

NM_001289807
NM_001289808
NM_001885
NM_001330379

...
Wikipedia