CREB-binding protein

CREBBP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1JSP, 1LIQ, 1RDT, 1WO3, 1WO4, 1WO5, 1WO6, 1WO7, 2D82, 2KJE, 2KWF, 2L84, 2L85, 2LXS, 2LXT, 2RNY, 3DWY, 3P1C, 3P1D, 3P1E, 3P1F, 3SVH, 4A9K, 4N3W, 4N4F, 4NR4, 4NR5, 4NR6, 4NR7, 4NYV, 4NYW, 4NYX, 4OUF, 4TQN, 4TS8, 4WHU, 5JEM, 5I8B, 5I89, 5I86, 4YK0, 5CGP, 5I8G, 2N1A, 5I83, 1ZOQ, 5DBM
Identifiers
Aliases	CREBBP, AW558298, CBP, CBP/p300, KAT3A, p300/CBP, RSTS, CREB binding protein
External IDs	MGI: 1098280 HomoloGene: 68393 GeneCards: CREBBP
Gene ontology Molecular function • transferase activity • RNA polymerase II transcription coactivator activity • MRF binding • RNA polymerase II transcription factor binding • transcription coactivator activity • zinc ion binding • p53 binding • transcription factor binding • chromatin binding • core promoter proximal region sequence-specific DNA binding • transcription cofactor activity • transcriptional repressor activity, RNA polymerase II transcription factor binding • signal transducer activity • metal ion binding • histone acetyltransferase activity • RNA polymerase II activating transcription factor binding • damaged DNA binding • transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding • protein binding • acetyltransferase activity • transferase activity, transferring acyl groups • peptide N-acetyltransferase activity • transcription factor activity, sequence-specific DNA binding Cellular component • cytoplasm • nucleoplasm • nuclear chromatin • histone acetyltransferase complex • nucleus • nuclear body Biological process • Notch signaling pathway • response to hypoxia • regulation of transcription, DNA-templated • cellular lipid metabolic process • protein complex assembly • rhythmic process • cellular response to UV • embryonic digit morphogenesis • N-terminal peptidyl-lysine acetylation • stimulatory C-type lectin receptor signaling pathway • negative regulation of transcription from RNA polymerase II promoter • transcription, DNA-templated • positive regulation of transcription, DNA-templated • regulation of smoothened signaling pathway • histone acetylation • regulation of transcription from RNA polymerase II promoter in response to hypoxia • regulation of cellular response to heat • transcription initiation from RNA polymerase II promoter • viral process • positive regulation of type I interferon production • signal transduction • protein acetylation • homeostatic process • beta-catenin-TCF complex assembly • regulation of apoptotic process • positive regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1387	12914
Ensembl	ENSG00000005339	ENSMUSG00000022521
UniProt	Q92793	P45481
RefSeq (mRNA)	NM_001079846 NM_004380	NM_001025432
RefSeq (protein)	NP_001073315 NP_004371	n/a
Location (UCSC)	Chr 16: 3.73 – 3.88 Mb	Chr 16: 4.08 – 4.21 Mb
PubMed search

1JSP, 1LIQ, 1RDT, 1WO3, 1WO4, 1WO5, 1WO6, 1WO7, 2D82, 2KJE, 2KWF, 2L84, 2L85, 2LXS, 2LXT, 2RNY, 3DWY, 3P1C, 3P1D, 3P1E, 3P1F, 3SVH, 4A9K, 4N3W, 4N4F, 4NR4, 4NR5, 4NR6, 4NR7, 4NYV, 4NYW, 4NYX, 4OUF, 4TQN, 4TS8, 4WHU, 5JEM, 5I8B, 5I89, 5I86, 4YK0, 5CGP, 5I8G, 2N1A, 5I83, 1ZOQ, 5DBM

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