Charge, Parity, and Time Reversal Symmetry is a fundamental symmetry of physical laws under the simultaneous transformations of charge conjugation (C), parity transformation (P), and time reversal (T). CPT is the only combination of C, P, and T that is observed to be an exact symmetry of nature at the fundamental level. The CPT theorem says that CPT symmetry holds for all physical phenomena, or more precisely, that any Lorentz invariant local quantum field theory with a Hermitian Hamiltonian must have CPT symmetry.
The CPT theorem appeared for the first time, implicitly, in the work of Julian Schwinger in 1951 to prove the connection between spin and statistics. In 1954, Gerhart Lüders and Wolfgang Pauli derived more explicit proofs, so this theorem is sometimes known as the Lüders–Pauli theorem. At about the same time, and independently, this theorem was also proved by John Stewart Bell. These proofs are based on the principle of Lorentz invariance and the principle of locality in the interaction of quantum fields. Subsequently Res Jost gave a more general proof in the framework of axiomatic quantum field theory.
Efforts during the late 1950s revealed the violation of P-symmetry by phenomena that involve the weak force, and there were well-known violations of C-symmetry as well. For a short time, the CP-symmetry was believed to be preserved by all physical phenomena, but that was later found to be false too, which implied, by CPT invariance, violations of T-symmetry as well.