CPSF-73

CPSF3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2I7T, 2I7V
Identifiers
Aliases	CPSF3, CPSF-73, CPSF73, cleavage and polyadenylation specific factor 3
External IDs	MGI: 1859328 HomoloGene: 6499 GeneCards: CPSF3
Gene ontology Molecular function • 5'-3' exonuclease activity • metal ion binding • endoribonuclease activity • protein binding • RNA binding • nuclease activity • endonuclease activity • hydrolase activity Cellular component • mRNA cleavage and polyadenylation specificity factor complex • intracellular ribonucleoprotein complex • nucleoplasm • nucleus Biological process • mRNA splicing, via spliceosome • termination of RNA polymerase II transcription • mRNA 3'-end processing by stem-loop binding and cleavage • mRNA processing • mRNA export from nucleus • mRNA polyadenylation • mRNA cleavage • mRNA 3'-end processing • RNA phosphodiester bond hydrolysis, endonucleolytic Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51692	54451
Ensembl	ENSG00000119203	ENSMUSG00000054309
UniProt	Q9UKF6	Q9QXK7
RefSeq (mRNA)	NM_016207 NM_001321833 NM_001321834 NM_001321835 NM_001321836	NM_018813
RefSeq (protein)	NP_001308762 NP_001308763 NP_001308764 NP_001308765 NP_057291	NP_061283
Location (UCSC)	Chr 2: 9.42 – 9.47 Mb	Chr 12: 21.29 – 21.32 Mb
PubMed search

2I7T, 2I7V

51692

54451

ENSG00000119203

ENSMUSG00000054309

Q9UKF6

Q9QXK7

NM_016207
NM_001321833
NM_001321834
NM_001321835
NM_001321836

NM_018813

NP_001308762
NP_001308763
NP_001308764
NP_001308765
NP_057291

NP_061283

Cleavage and polyadenylation specificity factor subunit 3 is a protein that in humans is encoded by the CPSF3 gene.

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Wikipedia