CLIC6

CLIC6
Identifiers
Aliases	CLIC6, CLIC1L, chloride intracellular channel 6
External IDs	MGI: 2146607 HomoloGene: 43154 GeneCards: CLIC6
Gene location (Human) Chr. Chromosome 21 (human) Band No data available Start 34,669,389 bp End 34,718,227 bp
Gene location (Mouse) Chr. Chromosome 16 (mouse) Band No data available Start 92,485,736 bp End 92,541,243 bp
Gene ontology Molecular function • voltage-gated ion channel activity • glutathione transferase activity • chloride channel activity Cellular component • integral component of membrane • plasma membrane • extracellular exosome • membrane • chloride channel complex • nucleus • cytoplasm Biological process • regulation of ion transmembrane transport • chloride transport • ion transport • glutathione metabolic process • chloride transmembrane transport • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	54102	209195
Ensembl	ENSG00000159212	ENSMUSG00000022949
UniProt	Q96NY7	Q8BHB9
RefSeq (mRNA)	NM_053277 NM_001317009	NM_172469
RefSeq (protein)	NP_001303938 NP_444507	NP_766057
Location (UCSC)	Chr 21: 34.67 – 34.72 Mb	Chr 21: 92.49 – 92.54 Mb
PubMed search

54102

209195

ENSG00000159212

ENSMUSG00000022949

Q96NY7

Q8BHB9

NM_053277
NM_001317009

NM_172469

NP_001303938
NP_444507

NP_766057

Chloride intracellular channel protein 6 is a protein that in humans is encoded by the CLIC6 gene.

This gene encodes a member of the chloride intracellular channel family of proteins. The gene is part of a large triplicated region found on chromosomes 1, 6, and 21. An alternatively spliced transcript variant has been described, but its biological validity has not been determined.

CLIC6 has been shown to interact with Dopamine receptor D3.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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