CK4

KRT4
Identifiers
Aliases	KRT4, CK-4, CK4, CYK4, K4, WSN1, Keratin 4
External IDs	MGI: 96701 HomoloGene: 20523 GeneCards: KRT4
Gene ontology Molecular function • protein binding • structural molecule activity Cellular component • cell surface • intermediate filament cytoskeleton • keratin filament • intermediate filament • nucleus • cytosol Biological process • epithelial cell differentiation • cytoskeleton organization • negative regulation of epithelial cell proliferation • keratinization • cornification Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3851	16682
Ensembl	ENSG00000170477	ENSMUSG00000059668
UniProt	P19013	P07744
RefSeq (mRNA)	NM_002272	NM_008475
RefSeq (protein)	NP_002263	NP_032501.2 NP_032501
Location (UCSC)	Chr 12: 52.81 – 52.81 Mb	Chr 15: 101.92 – 101.92 Mb
PubMed search

3851

16682

ENSG00000170477

ENSMUSG00000059668

P19013

P07744

NM_002272

NM_008475

NP_002263

NP_032501.2
NP_032501

Keratin, type I cytoskeletal 4 also known as cytokeratin-4 (CK-4) or keratin-4 (K4) is a protein that in humans is encoded by the KRT4 gene.

Keratin 4 is a type II cytokeratins. It is specifically found in differentiated layers of the mucosal and esophageal epithelia together with keratin 13. Mutations in the genes encoding this protein have been associated with White Sponge Nevus, characterized by , esophageal, and anal leukoplakia.

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Wikipedia