CIITA

Identifiers

CIITA, C2TA, CIITAIV, MHC2TA, NLRA, class II, major histocompatibility complex, transactivator, class II major histocompatibility complex transactivator

External IDs

OMIM: 600005 MGI: 108445 HomoloGene: 207 GeneCards: CIITA

Gene ontology
Molecular function	• transferase activity • DNA binding • nucleotide binding • protein complex binding • transcription coactivator activity • GTP binding • activating transcription factor binding • kinase activity • protein C-terminus binding • protein binding • transcription regulatory region DNA binding • transferase activity, transferring acyl groups • ATP binding
Cellular component	• PML body • nucleoplasm • nucleus
Biological process	• positive regulation of MHC class II biosynthetic process • regulation of transcription, DNA-templated • response to interferon-gamma • phosphorylation • interferon-gamma-mediated signaling pathway • response to antibiotic • negative regulation of transcription from RNA polymerase II promoter • transcription, DNA-templated • positive regulation of transcription, DNA-templated • immune response • negative regulation of transcription, DNA-templated • positive regulation of MHC class I biosynthetic process • negative regulation of collagen biosynthetic process • positive regulation of transcription from RNA polymerase II promoter
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


4261


12265

Ensembl


ENSG00000179583


ENSMUSG00000022504

UniProt


P33076


P79621

RefSeq (mRNA)


NM_000246 NM_001286402 NM_001286403


NM_001243760 NM_001243761 NM_007575 NM_001302618 NM_001302619

RefSeq (protein)


NP_000237 NP_001273331 NP_001273332


NP_001230689 NP_001230690 NP_001289547 NP_001289548 NP_031601

Location (UCSC)

Chr 16: 10.87 – 10.93 Mb

Chr 16: 10.49 – 10.53 Mb

PubMed search

NM_000246
NM_001286402
NM_001286403

NM_001243760
NM_001243761
NM_007575
NM_001302618
NM_001302619

NP_000237
NP_001273331
NP_001273332

NP_001230689
NP_001230690
NP_001289547
NP_001289548
NP_031601

...
Wikipedia