CHRNA7

CHRNA7
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5AFK, 5AFJ, 5AFL, 2MAW, 5AFN, 5AFM, 5AFH
Identifiers
Aliases	CHRNA7, CHRNA7-2, NACHRA7, cholinergic receptor nicotinic alpha 7 subunit
External IDs	MGI: 99779 HomoloGene: 593 GeneCards: CHRNA7
Gene ontology Molecular function • protein homodimerization activity • acetylcholine binding • acetylcholine-gated cation-selective channel activity • beta-amyloid binding • acetylcholine receptor activity • ion channel activity • chloride channel regulator activity • extracellular ligand-gated ion channel activity • toxic substance binding • ligand-gated ion channel activity Cellular component • integral component of membrane • acetylcholine-gated channel complex • postsynaptic membrane • membrane • plasma membrane • synapse • cell junction Biological process • response to hypoxia • cognition • cellular calcium ion homeostasis • ion transport • positive regulation of angiogenesis • ion transmembrane transport • activation of MAPK activity • positive regulation of cell proliferation • transport • calcium ion transport • signal transduction • synaptic transmission, cholinergic • memory • negative regulation of tumor necrosis factor production • response to nicotine • regulation of postsynaptic membrane potential • excitatory postsynaptic potential Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	1139	11441
Ensembl	n/a	ENSMUSG00000030525
UniProt	P36544	P49582
RefSeq (mRNA)	NM_000746 NM_001190455	NM_007390
RefSeq (protein)	NP_000737 NP_001177384	NP_031416.3 NP_031416
Location (UCSC)	Chr 15: 32.03 – 32.17 Mb	Chr 7: 63.1 – 63.21 Mb
PubMed search

5AFK, 5AFJ, 5AFL, 2MAW, 5AFN, 5AFM, 5AFH

1139

11441

n/a

ENSMUSG00000030525

P36544

P49582

NM_000746
NM_001190455

NM_007390

NP_000737
NP_001177384

NP_031416.3
NP_031416

Neuronal acetylcholine receptor subunit alpha-7, also known as nAChRα7, is a protein that in humans is encoded by the CHRNA7 gene. The protein encoded by this gene is a subunit of certain nicotinic acetylcholine receptors (nAchR).

...
Wikipedia